How Often Should You Wash Your Pajamas? Here's How to Tell When It's Time to Toss Them in the Laundry

TL;DR

Wash pajamas weekly in warm, soapy water (around 54°C).
Air out pajamas during the day between wears.
Change pajamas every three days for normal skin.
Wash more frequently if you sweat a lot, wear pajamas around the house, or have sensitive skin/skin conditions.
Natural materials like cotton and silk are better for longer wear between washes.
Wash immediately if pajamas have stains or are no longer fresh-smelling.

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