Sardinian Genetic Shield: Locals' DNA Hides Malaria Cure
The DNA of Sardinian inhabitants contains a gene that protects against malaria, according to the results of a study jointly conducted by the Institute of Genetics and Biomedical Research of the National Research Council (CNR) in Cagliari and the University of Sassari.
TL;DR
- Sardinians' DNA contains a gene variant that protects against malaria.
- The gene influences red blood cell development, hindering parasite growth.
- In lab conditions, the parasite could not multiply in cells with this variant and died.
- This genetic variant is common in Sardinia but absent in many malaria-endemic areas worldwide.
- Researchers suggest the gene likely evolved as a protective measure after humans migrated out of Africa.
- The study was a joint effort by the CNR in Cagliari and the University of Sassari, involving DNA analysis of about 7,000 volunteers.